Clinical and prognostic significances of cancer stem cell markers in gastric cancer patients: a systematic review and meta-analysis.

ABSTRACT:

Background

Gastric cancer (GC) is considered one of the most lethal malignancies worldwide, which is accompanied by a poor prognosis. Although reports regarding the importance of cancer stem cell (CSC) markers in gastric cancer progression have rapidly developed over the last few decades, their clinicopathological and prognostic values in gastric cancer still remain inconclusive. Therefore, the current meta-analysis aimed to quantitatively re-evaluate the association of CSC markers expression, overall and individually, with GC patients' clinical and survival outcomes.

Methods

Literature databases including PubMed, Scopus, ISI Web of Science, and Embase were searched to identify the eligible articles. Hazard ratios (HRs) or odds ratios (ORs) with 95% confidence intervals (CIs

SUBMITTER: Razmi M 

PROVIDER: S-EPMC7912890 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature