Standardized uptake values of ^99mTc-MDP in normal vertebrae assessed using quantitative SPECT/CT for differentiation diagnosis of benign and malignant bone lesions.

ABSTRACT:

Background

Quantitative bone SPECT/CT is useful for disease follow up and inter-patient comparison. For bone metastatic malignant lesions, spine is the most commonly invaded site. However, Quantitative studies with large sample size investigating all the segments of normal cervical, thoracic and lumbar vertebrae are seldom reported. This study was to evaluate the quantitative tomography of normal vertebrae using ^99mTc-MDP with SPECT/CT to investigate the feasibility of standardized uptake value (SUV) for differential diagnosis of benign and malignant bone lesions.

Methods

A retrospective study was carried out involving 221 patients (116 males and 105 females) who underwent SPECT/CT scan using ^99mTc-MDP. The maximum SUV (SUV_max), mean SUV (SUV

SUBMITTER: Qi N 

PROVIDER: S-EPMC7913396 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature