An update on the pharmacotherapeutic options and treatment strategies for systemic sclerosis.

ABSTRACT:

Introduction

Systemic sclerosis (SSc) is a multi-dimensional connective tissue disease of unknown etiology. Given the immense clinical complexity of SSc, the treatment of this condition is not standardized and considerable heterogeneity exists in SSc management approaches. The purpose of this article is to highlight novel therapeutic strategies and new medications under development for the treatment of systemic sclerosis (SSc).

Areas covered

Herein, the authors focus primarily on recently completed clinical trials and phase 3 and 4 clinical trials of therapeutic agents that show promise in SSc. This review is organized by the clinical complications that occur in SSc, for which novel treatment strategies are under study.

Expert opinion

Combining therapies to address th

SUBMITTER: McMahan ZH 

PROVIDER: S-EPMC7913471 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature