Chemical Profiles and Pharmacological Properties with in Silico Studies on Elatostema papillosum Wedd.

ABSTRACT: The current study attempted, for the first time, to qualitatively and quantitatively determine the phytochemical components of Elatostema papillosum methanol extract and their biological activities. The present study represents an effort to correlate our previously reported biological activities with a computational study, including molecular docking, and ADME/T (absorption, distribution, metabolism, and excretion/toxicity) analyses, to identify the phytochemicals that are potentially responsible for the antioxidant, antidepressant, anxiolytic, analgesic, and anti-inflammatory activities of this plant. In the gas chromatography-mass spectroscopy analysis, a total of 24 compounds were identified, seven of which were documented as being bioactive based on their binding affinities. These seve

SUBMITTER: Uddin MZ 

PROVIDER: S-EPMC7913918 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature