Accelerated Wound Closure of Deep Partial Thickness Burns with Acellular Fish Skin Graft.

ABSTRACT: Thermal injuries are caused by exposure to a variety of sources, and split thickness skin grafts are the gold standard treatment for severe burns; however, they may be impossible when there is no donor skin available. Large total body surface area burns leave patients with limited donor site availability and create a need for treatments capable of achieving early and complete coverage that can also retain normal skin function. In this preclinical trial, two cellular and tissue based products (CTPs) are evaluated on twenty-four 5 × 5 deep partial thickness (DPT) burn wounds. Using appropriate pain control methods, DPT burn wounds were created on six anesthetized Yorkshire pigs. Wounds were excised one day post-burn and the bleeding wound beds were subsequently treated with omega-3-rich acel

SUBMITTER: Stone R 

PROVIDER: S-EPMC7915828 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature