Radiotherapy in the Management of Pediatric and Adult Osteosarcomas: A Multi-Institutional Cohort Analysis.

ABSTRACT:

Background

Due to the rarity of osteosarcoma and limited indications for radiotherapy (RT), data on RT for this tumor are scarce. This study aimed to investigate the utilization of RT for osteosarcomas in the recent 20 years and to identify factors related to patients' response to radiation.

Methods

We performed a retrospective analysis of patients irradiated for osteosarcoma treatment. We planned to assess differences in the utilization of RT between the periods of 2000-2010 and 2011-2020, identify the risk factors associated with local progression (LP), determine whether RT-related parameters are associated with LP, and calculate patients' survival.

Results

A total of 126 patients with osteosarcoma who received 181 RT treatments were identified. We found a differenc

SUBMITTER: Spalek MJ 

PROVIDER: S-EPMC7916348 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature