Ontology highlight
ABSTRACT:
SUBMITTER: Ok CY
PROVIDER: S-EPMC7916510 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Ok Chang Youp CY Park Sera S Jang Hye-Ock HO Takata Takashi T Lee Ok-Hee OH Bae Moon-Kyoung MK Bae Soo-Kyung SK
Antioxidants (Basel, Switzerland) 20210210 2
FK866 possesses various functional properties, such as anti-angiogenic, anti-cancer, and anti-inflammatory activities. We previously demonstrated that premature senescence of human dental pulp cells (hDPCs) was induced by hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>). The present study aimed to investigate whether H<sub>2</sub>O<sub>2</sub>-induced premature senescence of hDPCs is affected by treatment with FK866. We found that FK866 markedly inhibited the senescent characteristics of hDPCs aft ...[more]