Adipose Tissue Gene Expression of Entire Male, Immunocastrated and Surgically Castrated Pigs.

ABSTRACT: Differences in adipose tissue deposition and properties between pig male sex categories, i.e., entire males (EM), immunocastrates (IC) and surgical castrates (SC) are relatively well-characterized, whereas the underlying molecular mechanisms are still not fully understood. To gain knowledge about the genetic regulation of the differences in adipose tissue deposition, two different approaches were used: RNA-sequencing and candidate gene expression by quantitative PCR. A total of 83 differentially expressed genes were identified between EM and IC, 15 between IC and SC and 48 between EM and SC by RNA-sequencing of the subcutaneous adipose tissue. Comparing EM with IC or SC, upregulated genes related to extracellular matrix dynamics and adipogenesis, and downregulated genes involved in the con

SUBMITTER: Poklukar K 

PROVIDER: S-EPMC7916650 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature