Estimation and inference for semi-competing risks based on data from a nested case-control study.

ABSTRACT: In semi-competing risks, the occurrence of some non-terminal event is subject to a terminal event, usually death. While existing methods for semi-competing risks data analysis assume complete information on all relevant covariates, data on at least one covariate are often not readily available in practice. In this setting, for standard univariate time-to-event analyses, researchers may choose from several strategies for sub-sampling patients on whom to collect complete data, including the nested case-control study design. Here, we consider a semi-competing risks analysis through the reuse of data from an existing nested case-control study for which risk sets were formed based on either the non-terminal or the terminal event. Additionally, we introduce the supplemented nested case-contro

SUBMITTER: Jazic I 

PROVIDER: S-EPMC7916743 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature