Reciprocally-Coupled Gating: Strange Loops in Bioenergetics, Genetics, and Catalysis.

ABSTRACT: Bioenergetics, genetic coding, and catalysis are all difficult to imagine emerging without pre-existing historical context. That context is often posed as a "Chicken and Egg" problem; its resolution is concisely described by de Grasse Tyson: "The egg was laid by a bird that was not a chicken". The concision and generality of that answer furnish no details-only an appropriate framework from which to examine detailed paradigms that might illuminate paradoxes underlying these three life-defining biomolecular processes. We examine experimental aspects here of five examples that all conform to the same paradigm. In each example, a paradox is resolved by coupling "if, and only if" conditions for reciprocal transitions between levels, such that the consequent of the first test is the antecedent f

SUBMITTER: Carter CW 

PROVIDER: S-EPMC7916928 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature