Comparative Genomics of Mycobacterium avium Subspecies Paratuberculosis Sheep Strains.

ABSTRACT: Mycobacterium avium subspecies paratuberculosis (MAP) is the aetiological agent of Johne's disease (JD), a chronic enteritis that causes major losses to the global livestock industry. Further, it has been associated with human Crohn's disease. Several strains of MAP have been identified, the two major groups being sheep strain MAP, which includes the Type I and Type III sub-lineages, and the cattle strain or Type II MAP lineage, of which bison strains are a sub-grouping. Major genotypic, phenotypic and pathogenic variations have been identified in prior comparisons, but the research has predominately focused on cattle strains of MAP. In countries where the sheep industries are more prevalent, however, such as Australia and New Zealand, ovine JD is a substantial burden. An inf

SUBMITTER: Mizzi R 

PROVIDER: S-EPMC7917049 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature