Proposed virulence-associated genes of Streptococcus suis isolates from the United States serve as predictors of pathogenicity.

ABSTRACT:

Background

There is limited information on the distribution of virulence-associated genes (VAGs) in U.S. Streptococcus suis isolates, resulting in little understanding of the pathogenic potential of these isolates. This lack also reduces our understanding of the epidemiology associated with S. suis in the United States and thus affects the efficiency of control and prevention strategies. In this study we applied whole genome sequencing (WGS)-based approaches for the characterization of S. suis and identification of VAGs.

Results

Of 208 S. suis isolates classified as pathogenic, possibly opportunistic, and commensal pathotypes, the genotype based on the classical VAGs (epf, mrp, and sly encoding the extracellular protein factor, muramidase-release protein, and suilysin, respe

SUBMITTER: Estrada AA 

PROVIDER: S-EPMC7917538 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature