Cetyltrimethylammonium Bromide (CTAB)-Loaded SiO2-Ag Mesoporous Nanocomposite as an Efficient Antibacterial Agent.

ABSTRACT: To date, Ag-based nanomaterials have demonstrated a high potential to overcome antibiotic resistance issues. However, bare Ag nanomaterials are prone to agglomeration in the biological environment, which results in a loss of antibacterial activity over time. Furthermore, it is still challenging to collect small-sized Ag nanomaterials right after the synthesis process. In this study, spherical-shaped Ag nanoparticles (NPs) (~6-10 nm) were attached on the surface of cetyltrimethylammonium bromide (CTAB)-loaded mesoporous silica nanoparticles (MSNs) (~100-110 nm). Antibacterial activity tests suggested that the obtained nanocomposite can be used as a highly efficient antibacterial agent against both Gram-negative and Gram-positive bacterial strains. The minimum inhibitory concentration (MIC)

SUBMITTER: Abduraimova A 

PROVIDER: S-EPMC7917824 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature