Effects of Gene-Environment Interaction on Obesity among Chinese Adults Born in the Early 1960s.

ABSTRACT: The prevalence of obesity has been increasing sharply and has become a serious public health problem worldwide. Gene-environment interaction in obesity is a relatively new field, and little is known about it in Chinese adults. This study aimed to provide the effects of gene-environment interaction on obesity among Chinese adults. A stratified multistage cluster sampling method was conducted to recruit participants from 150 surveillance sites. Subjects born in 1960, 1961 and 1963 were selected. An exploratory factor analysis was used to classify the environmental factors. The interaction of single nucleotide polymorphisms (SNPs) and environmental factors on body mass index (BMI) and waist circumference were analyzed using a general linear model. A multiple logistic regression model combined

SUBMITTER: Gong W 

PROVIDER: S-EPMC7918169 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature