Evidence for long memory in focal seizure duration.

ABSTRACT:

Objective

A major source of disability for people with epilepsy involves uncertainty surrounding seizure timing and severity. Although patients often report that long seizure-free intervals are followed by more severe seizures, there is little experimental evidence supporting this observation. Optimal characterization of seizure severity is debated; however, seizure duration is associated with seizure type and can be quantified in electrographic recordings as a limited proxy of clinical seizure severity. Here, using chronic intracranial electroencephalography (cEEG), we investigate the relationship between interseizure interval (ISI) and duration of the subsequent seizure.

Methods

We performed a retrospective analysis of 14 subjects implanted with a responsive neurostimulati

SUBMITTER: Fan JM 

PROVIDER: S-EPMC7918332 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature