Investigating the Intervention Parameters of Endogenous Paired Associative Stimulation (ePAS).

ABSTRACT: Advances in our understanding of neural plasticity have prompted the emergence of neuromodulatory interventions, which modulate corticomotor excitability (CME) and hold potential for accelerating stroke recovery. Endogenous paired associative stimulation (ePAS) involves the repeated pairing of a single pulse of peripheral electrical stimulation (PES) with endogenous movement-related cortical potentials (MRCPs), which are derived from electroencephalography. However, little is known about the optimal parameters for its delivery. A factorial design with repeated measures delivered four different versions of ePAS, in which PES intensities and movement type were manipulated. Linear mixed models were employed to assess interaction effects between PES intensity (suprathreshold (Hi) and motor thr

SUBMITTER: Alder G 

PROVIDER: S-EPMC7918620 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature