Transcriptomic Responses of the Honey Bee Brain to Infection with Deformed Wing Virus.

ABSTRACT: Managed colonies of European honey bees (Apis mellifera) are under threat from Varroa destructor mite infestation and infection with viruses vectored by mites. In particular, deformed wing virus (DWV) is a common viral pathogen infecting honey bees worldwide that has been shown to induce behavioral changes including precocious foraging and reduced associative learning. We investigated how DWV infection of bees affects the transcriptomic response of the brain. The transcriptomes of individual brains were analyzed using RNA-Seq after experimental infection of newly emerged adult bees with DWV. Two analytical methods were used to identify differentially expressed genes from the ~15,000 genes in the Apis mellifera genome. The 269 genes that had increased expression in DWV

SUBMITTER: Pizzorno MC 

PROVIDER: S-EPMC7918736 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature