Histological chorioamnionitis is associated with an increased risk of wheezing in preterm children less than 34 gestational weeks.

ABSTRACT:

Background

Chorioamnionitis is associated with various neonatal short- and long-term morbidities. The effect of chorioamnionitis on premature children's outcomes remains controversial. The aim of this study is to investigate the relationship between histological chorioamnionitis (HCA) and physiological development, wheezing, and atopic diseases in preterm children.

Methods

Singleton, preterm children (< 34 weeks), whose mother underwent pathological placental examinations, were retrospectively enrolled and the outcomes were assessed at 24-40 months during follow-up. Wheezing and atopic diseases including eczema, food allergies, and allergic rhinitis were screened by a questionnaire along with medical diagnosis. Anthropometric indexes and blood pressure were measured. Cogniti

SUBMITTER: Wang X 

PROVIDER: S-EPMC7919088 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature