Coronary flow impairment in asymptomatic patients with early stage type-2 diabetes: Detection by FFR_CT.

ABSTRACT:

Purpose

To determine the occurrence of physiological significant coronary artery disease (CAD) by coronary CT angiography (CTA) derived fractional flow reserve (FFR_CT) in asymptomatic patients with a new diagnosis (<1 year) of type-2 diabetes mellitus (T2DM).

Methods

FFR_CT-analysis was performed from standard acquired coronary CTA data sets. The per-patient minimum distal FFR_CT-value (d-FFR_CT) in coronary vessels (diameter ⩾1.8 mm) was registered. The threshold for categorizing FFR_CT-analysis as abnormal was a d-FFR_CT ⩽0.75. Total plaque volume and volumes of calcified plaque, non-calcified plaque, and low-density non-calcified plaque (LD-NCP) were assessed by quantitative plaque analysis.

Results

Overa

SUBMITTER: Mrgan M 

PROVIDER: S-EPMC7919222 | biostudies-literature | 2020 Sep-Oct

REPOSITORIES: biostudies-literature