Indeterminate pulmonary nodules are not associated with worse overall survival in Ewing Sarcoma.

ABSTRACT:

Aim

Lung metastases are a negative prognostic factor in Ewing sarcoma, however, the incidence and significance of sub-centimetre pulmonary nodules at diagnosis is unclear. The aims of this study were to (1): determine the incidence of indeterminate pulmonary nodules (IPNs) in patients diagnosed with Ewing sarcoma (2); establish the impact of IPNs on overall and metastasis-free survival and (3) identify patient, oncological and radiological factors that correlate with poorer prognosis in patients that present with IPNs on their staging chest CT.

Materials & methods

Between 2008 and 2016, 173 patients with a first presentation of Ewing sarcoma of bone were retrospectively identified from an institutional database. Staging and follow-up chest CTs for all patients with IPN were

SUBMITTER: Tsoi KM 

PROVIDER: S-EPMC7920159 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature