Multiple positron emission tomography tracers for use in the classification of gliomas according to the 2016 World Health Organization criteria.

ABSTRACT:

Background

The molecular diagnosis of gliomas such as isocitrate dehydrogenase (IDH) status (wild-type [wt] or mutation [mut]) is especially important in the 2016 World Health Organization (WHO) classification. Positron emission tomography (PET) has afforded molecular and metabolic diagnostic imaging. The present study aimed to define the interrelationship between the 2016 WHO classification of gliomas and the integrated data from PET images using multiple tracers, including ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG), ¹¹C-methionine (¹¹C-MET), ¹⁸F-fluorothymidine (¹⁸F-FLT), and ¹⁸F-fluoromisonidazole (¹⁸F-FMISO).

Methods

This retrospective, single-center study comprised 113 patients with newly diag

SUBMITTER: Miyake K 

PROVIDER: S-EPMC7920529 | biostudies-literature | 2021 Jan-Dec

REPOSITORIES: biostudies-literature