Local and Travel-Associated Transmission of Tuberculosis at Central Western Border of Brazil, 2014-2017.

ABSTRACT: International migrants are at heightened risk for tuberculosis (TB) disease. Intensified incarceration at international borders may compound population-wide TB risk. However, few studies have investigated the contributions of migration, local transmission, or prisons in driving incident TB at international borders. We conducted prospective population-based genomic surveillance in 3 cities along Brazil's central western border from 2014-2017. Although most isolates (89/132; 67%) fell within genomic transmission clusters, genetically unique isolates disproportionately occurred among participants with recent international travel (17/42; 40.5%), suggesting that both local transmission and migration contribute to incident TB. Isolates from 40 participants with and 76 without an incarceration hi

SUBMITTER: Walter KS 

PROVIDER: S-EPMC7920644 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature