Protein dataset of immortalized keratinocyte HaCaT cells and normal human keratinocytes.

ABSTRACT: Learning of the molecular mechanisms of the pathological processes development in the normal human keratinocytes (NHK) are difficult. Immortalized keratinocytes HaCaT are often used as an analogue of NHK since they have a number of advantages over the latter - they do not require the presence of growth and differentiation factors in the medium, have unlimited potential for proliferation, demonstrate stable phenotype regardless of the number of passages [1]. Taking into account the properties and characteristics of the HaCaT line, these cells can be considered as a promising experimental model for research of various physiological processes occurring in human keratinocytes. However, to understand the limitations of such an experimental model, a detailed comparative characterization of HaCaT

SUBMITTER: Rusanov AL 

PROVIDER: S-EPMC7921465 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature