Inter-site and interpersonal diversity of salivary and tongue microbiomes, and the effect of oral care tablets.

ABSTRACT: Background: Oral microbiota has been linked to both health and diseases. Specifically, tongue-coating microbiota has been implicated in aspiration pneumonia and halitosis. Approaches altering one's oral microbiota have the potential to improve oral health and prevent diseases. Methods: Here, we designed a study that allows simultaneous monitoring of the salivary and tongue microbiomes during an intervention on the oral microbiota. We applied this study design to evaluate the effect of single-day use of oral care tablets on the oral microbiome of 10 healthy individuals. Tablets with or without actinidin, a protease that reduces biofilm formation in vitro, were tested. Results: Alpha diversity of the tongue microbiome was significantly lower than that of the saliv

SUBMITTER: Maruyama H 

PROVIDER: S-EPMC7921892 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature