Staphylococcal Communities on Skin Are Associated with Atopic Dermatitis and Disease Severity.

ABSTRACT: The skin microbiota of atopic dermatitis (AD) patients is characterized by increased Staphylococcus aureus colonization, which exacerbates disease symptoms and has been linked to reduced bacterial diversity. Skin bacterial communities in AD patients have mostly been described at family and genus levels, while species-level characterization has been limited. In this study, we investigated the role of the bacteria belonging to the Staphylococcus genus using targeted sequencing of the tuf gene with genus-specific primers. We compared staphylococcal communities on lesional and non-lesional skin of AD patients, as well as AD patients with healthy controls, and determined the absolute abundance of bacteria present at each site. We observed that the staphylococcal community,

SUBMITTER: Edslev SM 

PROVIDER: S-EPMC7921937 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature