Severe Hypoglycemia Risk With Long-Acting Insulin Analogs vs Neutral Protamine Hagedorn Insulin.

ABSTRACT:

Importance

Previous studies have found that the risk of severe hypoglycemia does not differ between long-acting insulin analogs and neutral protamine Hagedorn (NPH) insulin in patients with type 2 diabetes. However, these studies did not focus on patients 65 years or older, who are at an increased risk for hypoglycemia, or did not include patients with concomitant prandial insulin use.

Objective

To examine the risk of emergency department (ED) visits or hospitalizations for hypoglycemia among older community-residing patients with type 2 diabetes who initiated long-acting insulin or NPH insulin in real-world settings.

Design, setting, and participants

This retrospective, new-user cohort study assessed Medicare beneficiaries 65 years or older who initiated insulin glar

SUBMITTER: Bradley MC 

PROVIDER: S-EPMC7922234 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature