Development of Gold Nanoparticle Micropatterns for the Electrical Detection of Proteins.

ABSTRACT: Protein analysis can be used to efficiently detect the early stages of various diseases. However, conventional protein detection platforms require expensive or complex equipment, which has been a major obstacle to their widespread application. In addition, uncertain signals from non-specific adhesion interfere with the precise interpretation of the results. To overcome these problems, the development of a technique that can detect the proteins in a simple method is needed. In this study, a platform composed of gold nanoparticles (GNPs) was fabricated through a simple imprinting method for protein detection. The corrugated surface naturally formed by the nanoparticle assemblies simultaneously increases the efficiency of adhesion and binding with analytes and reduces undesired interactions.

SUBMITTER: Lim G 

PROVIDER: S-EPMC7922899 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature