Effects of hyperbaric environment on endurance and metabolism are exposure time-dependent in well-trained mice.

ABSTRACT: Hyperbaric exposure (1.3 atmospheres absolute with 20.9% O₂ ) for 1 h a day was shown to improve exercise capacity. The present study was designed to reveal whether the daily exposure time affects exercise performance and metabolism in skeletal and cardiac muscles. Male mice in the training group were housed in a cage with a wheel activity device for 7 weeks from 5 weeks old. Trained mice were then subjected to hybrid training (HT, endurance exercise for 30 min followed by sprint interval exercise for 30 min). Hyperbaric exposure was applied following daily HT for 15 min (15HT), 30 min (30HT), or 60 min (60HT) for 4 weeks. In the endurance capacity test, maximal work values were significantly increased by 30HT and 60HT. In the left ventricle (LV), activity levels of 3-hydroxyacy

SUBMITTER: Suzuki J 

PROVIDER: S-EPMC7923584 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature