"Include me if you can"-reasons for low enrollment of pediatric patients in a psychopharmacological trial.

ABSTRACT:

Background

Low recruitment in clinical trials is a common and costly problem which undermines medical research. This study aimed to investigate the challenges faced in recruiting children and adolescents with obsessive-compulsive disorder and autism spectrum disorder for a randomized, double-blind, placebo-controlled clinical trial and to analyze reasons for non-participation. The trial was part of the EU FP7 project TACTICS (Translational Adolescent and Childhood Therapeutic Interventions in Compulsive Syndromes).

Methods

Demographic data on pre-screening patients were collected systematically, including documented reasons for non-participation. Findings were grouped according to content, and descriptive statistical analyses of the data were performed.

Results

In tot

SUBMITTER: Niemeyer L 

PROVIDER: S-EPMC7923624 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature