Fermentative production of enantiopure (S)-linalool using a metabolically engineered Pantoea ananatis.

ABSTRACT:

Background

Linalool, an acyclic monoterpene alcohol, is extensively used in the flavor and fragrance industries and exists as two enantiomers, (S)- and (R)-linalool, which have different odors and biological properties. Linalool extraction from natural plant tissues suffers from low product yield. Although linalool can also be chemically synthesized, its enantioselective production is difficult. Microbial production of terpenes has recently emerged as a novel, environmental-friendly alternative. Stereoselective production can also be achieved using this approach via enzymatic reactions. We previously succeeded in producing enantiopure (S)-linalool using a metabolically engineered Pantoea ananatis, a member of the Enterobacteriaceae family of bacteria, via the heterologous mevalonat

SUBMITTER: Nitta N 

PROVIDER: S-EPMC7923825 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature