High-Spatial-Resolution 3D Whole-Heart MRI T2 Mapping for Assessment of Myocarditis.

ABSTRACT: Background Clinical guidelines recommend the use of established T2 mapping sequences to detect and quantify myocarditis and edema, but T2 mapping is performed in two dimensions with limited coverage and repetitive breath holds. Purpose To assess the reproducibility of an accelerated free-breathing three-dimensional (3D) whole-heart T2 MRI mapping sequence in phantoms and participants without a history of cardiac disease and to investigate its clinical performance in participants with suspected myocarditis. Materials and Methods Eight participants (three women, mean age, 31 years ± 4 [standard deviation]; cohort 1) without a history of cardiac disease and 25 participants (nine women, mean age, 45 years ± 17; cohort 2) with clinically suspected myocarditis underwent accelerated free-breathin

SUBMITTER: Bustin A 

PROVIDER: S-EPMC7924517 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature