Association of proteinuria with incident atrial fibrillation in the general Japanese population.

ABSTRACT:

Background

Although proteinuria has been associated with incident atrial fibrillation (AF) in Western countries, the association has not been investigated in the general Japanese population.

Methods

Participants aged ≥40 years who underwent the Japanese specific health check-up in Kanazawa City in 2013 and who completed a urine dipstick test were included in this study. Exposure was considered as presence or absence of proteinuria (≥1+). The outcome was incident AF confirmed by 12-lead electrocardiography. The Cox proportional hazard model was used to compute hazard ratio (HR) of proteinuria (≥1+) for incident AF after adjustment for traditional risk factors. We also completed stratified analyses by baseline characteristics.

Results

A total of 37,910 participants aged

SUBMITTER: Tanaka Y 

PROVIDER: S-EPMC7924545 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature