3D UTE bicomponent imaging of cortical bone using a soft-hard composite pulse for excitation.

ABSTRACT:

Purpose

To evaluate 3D UTE bicomponent imaging of cortical bone ex vivo and in vivo using a newly designed soft-hard composite pulse for excitation.

Methods

Chemical shift artifacts, presenting as fat-water oscillation or combination-induced signal oscillation, significantly reduce the accuracy of quantitative UTE bicomponent analysis of cortical bone. To achieve fat suppression for more reliable bicomponent analysis, a newly developed soft-hard excitation pulse was used with UTE imaging and compared with a single rectangular pulse excitation without and with a conventional fat saturation (FatSat) module. These 3 sequences were applied to 8 bovine bone samples without marrow fat, 3 bovine bone samples with marrow fat, and tibial midshafts of 5 healthy human volunteers. Bicom

SUBMITTER: Li L 

PROVIDER: S-EPMC7924727 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature