Contemporary utilization patterns and outcomes of thrombolytic administration for ischemic stroke among patients with cancer.

ABSTRACT:

Background

Thrombolytic therapy significantly improves outcomes among patients with acute ischemic stroke. While cancer outcomes have dramatically improved, the utilization, safety, and mortality outcomes of patients with cancer who receive thrombolytic therapy for acute ischemic stroke are unknown.

Methods

Using a national database, we identified all hospitalizations for acute ischemic stroke requiring thrombolytic therapy between 2003 and 2015. Patients with contraindications to thrombolytic therapy were excluded. Following propensity score matching for comorbidity burden, trends in thrombolytic therapy use and its effect on in-hospital mortality, intracranial or all-cause bleeding, and the combined endpoint of mortality and all-cause bleeding, by presence/absence of cance

SUBMITTER: Owusu-Guha J 

PROVIDER: S-EPMC7924729 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature