Resistin is a risk factor for all-cause mortality in elderly Finnish population: A prospective study in the OPERA cohort.

ABSTRACT:

Objective

Resistin is a small, cysteine-rich proinflammatory molecule that is primarily secreted by peripheral blood mononuclear cells and macrophages in humans. Previous studies have shown resistin to participate in various pathological processes including atherosclerosis and cancer progression but not many studies have assessed the role of resistin as a risk factor for all-cause mortality. The objective of this prospective study was to evaluate whether resistin predicts mortality among elderly Finnish people.

Methods

The study population consisted of 599 elderly (71.7 ± 5.4 years) patients and the follow-up was approximately six years. A thorough clinical examination including anthropometric and other clinical measurements such as blood pressure as well as various laborato

SUBMITTER: Parkkila K 

PROVIDER: S-EPMC7924753 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature