Red blood cell transfusions and potentially related morbidities in neonates under 32 weeks' gestation.

ABSTRACT:

Background

Preterm neonates are likely to require red blood cell (RBC) transfusion, and extremely low birth weight infants almost invariably receive multiple transfusions. Transfusion-reduction strategies can reduce transfusion rates, and might diminish certain adverse outcomes associated with transfusions.

Materials and methods

In a single centre, we retrospectively evaluated RBC transfusion rates among preterm infants ≤32 weeks' gestational age (GA), over a 6-year period before and after adopting national transfusion-reduction strategies. We compared demographic data, adverse events, and outcomes between transfused vs not-transfused neonates. Univariate logistic regression was used to evaluate associations between dichotomous outcomes and number of transfusions, and day of

SUBMITTER: D'Amato G 

PROVIDER: S-EPMC7925223 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature