Racial disparities in survival outcomes among breast cancer patients by molecular subtypes.

ABSTRACT:

Purpose

Differences in tumor biology, genomic architecture, and health care delivery patterns contribute to the breast cancer mortality gap between White and Black patients in the US. Although this gap has been well documented in previous literature, it remains uncertain how large the actual effect size of race is for different survival outcomes and the four breast cancer subtypes.

Methods

We established a breast cancer patient cohort at the University of Chicago Comprehensive Cancer Center. We chose five major survival outcomes to study: overall survival, recurrence-free survival, breast-cancer-specific survival, time-to-recurrence and post-recurrence survival. Cox proportional hazards models were used to estimate the hazard ratios between Black and White patients, adjustin

SUBMITTER: Zhao F 

PROVIDER: S-EPMC7925344 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature