Cell Therapy for Critical Limb Ischemia: Advantages, Limitations, and New Perspectives for Treatment of Patients with Critical Diabetic Vasculopathy.

ABSTRACT:

Purpose of review

To provide a highlight of the current state of cell therapy for the treatment of critical limb ischemia in patients with diabetes.

Recent findings

The global incidence of diabetes is constantly growing with consequent challenges for healthcare systems worldwide. In the UK only, NHS costs attributed to diabetic complications, such as peripheral vascular disease, amputation, blindness, renal failure, and stroke, average £10 billion each year, with cost pressure being estimated to get worse. Although giant leaps forward have been registered in the scope of early diagnosis and optimal glycaemic control, an effective treatment for critical limb ischemia is still lacking. The present review aims to provide an update of the ongoing work in the field of regenerativ

SUBMITTER: Gu Y 

PROVIDER: S-EPMC7925447 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature