Molecular Characterization of bla _{IMP - 4} -Carrying Enterobacterales in Henan Province of China.

ABSTRACT: Carbapenem-resistant Enterobacterales (CRE) pose a serious threat to clinical management and public health. We investigated the molecular characteristics of 12 IMP-4 metallo-β-lactamase-producing strains, namely, 5 Enterobacter cloacae, 3 Escherichia coli, 2 Klebsiella pneumoniae, and 2 Citrobacter freundii. These strains were collected from a tertiary teaching hospital in Zhengzhou from 2013 to 2015. The minimum inhibitory concentration (MIC) results showed that each bla _{IMP - 4}-positive isolate was multidrug-resistant (MDR) but susceptible to colistin. All of the E. coli belonged to ST167, two C. freundii isolates belonged to ST396, and diverse ST types were identified in E. cloacae and

SUBMITTER: Liu W 

PROVIDER: S-EPMC7925629 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature