Associations between race and survival in pediatric patients with diffuse large B-cell lymphoma.

ABSTRACT:

Background

The purpose of this study was to examine the factors associated with disparities in overall survival (OS) by race in pediatric diffuse large B-cell lymphoma (DLBCL) patients.

Methods

We evaluated clinical features and survival among patients ≤21 years of age diagnosed with stage I-IV DLBCL from 2004 to 2014 from the National Cancer Database (NCDB) using a multivariable Cox proportional hazards model.

Results

Among 1386 pediatric patients with DLBCL, 1023 patients met eligibility criteria. In unadjusted analysis, Black patients had a significantly higher overall death rate than White patients (HR_{Black vs. White} 1.51; 95% CI: 1.02-2.23, p = 0.041). The survival disparity did not remain significant in adjusted analysis, though controlling for covari

SUBMITTER: Khullar K 

PROVIDER: S-EPMC7926019 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature