Loss of lower extremity muscle strength based on diabetic polyneuropathy in older patients with type 2 diabetes: Multicenter Survey of the Isometric Lower Extremity Strength in Type 2 Diabetes: Phase 2 study.

ABSTRACT:

Aims/introduction

Diabetic polyneuropathy (DPN) is a factor that reduces lower extremity muscle strength (LEMS) in older type 2 diabetes patients. This relationship remains unclear in longitudinal studies. Therefore, we longitudinally investigated the apparent effects of DPN on changes in LEMS. Furthermore, we cross-sectionally examined relationships among DPN, LEMS, mobility and health-related quality of life.

Materials and methods

Bodyweight-normalized (relative) knee extension force (KEF) was examined in 51 DPN and 54 non-DPN patients (68.9 ± 5.6 and 70.2 ± 5.9 years, respectively) at baseline and follow up at 3.6 ± 0.6 years. At follow up, mobility was measured using a 25-question geriatric locomotive function scale. Health-related quality of life was assessed using the

SUBMITTER: Nomura T 

PROVIDER: S-EPMC7926230 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature