Treatment effects in randomised trials using routinely collected data for outcome assessment versus traditional trials: meta-research study.

ABSTRACT:

Objective

To compare effect estimates of randomised clinical trials that use routinely collected data (RCD-RCT) for outcome ascertainment with traditional trials not using routinely collected data.

Design

Meta-research study.

Data source

Studies included in the same meta-analysis in a Cochrane review.

Eligibility criteria for study selection

Randomised clinical trials using any type of routinely collected data for outcome ascertainment, including from registries, electronic health records, and administrative databases, that were included in a meta-analysis of a Cochrane review on any clinical question and any health outcome together with traditional trials not using routinely collected data for outcome measurement.

Review methods

Effect estimates from tr

SUBMITTER: Mc Cord KA 

PROVIDER: S-EPMC7926294 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature