High-Order Fiber Mode Beam Parameter Optimization for Transport and Rotation of Single Cells.

ABSTRACT: Optical tweezers are becoming increasingly important in biomedical applications for the trapping, propelling, binding, and controlled rotation of biological particles. These capabilities enable applications such as cell surgery, microinjections, organelle extraction and modification, and preimplantation genetic diagnosis. In particular, optical fiber-based tweezers are compact, highly flexible, and can be readily integrated into lab-on-a-chip devices. Taking advantage of the beam structure inherent in high-order modes of propagation in optical fiber, LP11, LP21, and LP31 fiber modes can generate structured radial light fields with two or more concentrations in the cross-section of a beam, forming multiple traps for bioparticles with a single optical fiber. In this paper, we report the dyna

SUBMITTER: Shan Z 

PROVIDER: S-EPMC7926556 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature