Efficacy of serratiopeptidase after impacted third molar surgery: a randomized controlled clinical trial.

ABSTRACT:

Background

Serratiopeptidase has been clinically used in controlling surgical and non-surgical inflammatory conditions. This study was conducted to assess the therapeutic effect of Serratiopeptidase in patients undergoing surgical removal of impacted mandibular third molar.

Methods

This randomized clinical trial investigated the efficacy of Serratiopeptidase and Paracetamol after surgical removal of impacted third molar for 5 days (n = 67) as compared with an equivalent dose of placebo and Paracetamol (n = 66). Outcome measures were reported pain, trismus and swelling using Laskin method. All outcome measures were recorded on days 0, 1, 2, 4, and 5 post-surgeries.

Results

In this clinical trail 133 patients (mean age 23 years, 54% female) completed the study. Baseline

SUBMITTER: Tamimi Z 

PROVIDER: S-EPMC7927242 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature