Spectroscopic photoacoustic imaging of cervical tissue composition in excised human samples.

ABSTRACT:

Objective

Cervical remodeling is an important component in determining the pathway of parturition; therefore, assessing changes in cervical tissue composition may provide information about the cervix's status beyond the measurement of cervical length. Photoacoustic imaging is a non-invasive ultrasound-based technology that captures acoustic signals emitted by tissue components in response to laser pulses. This optical information allows for the determination of the collagen-to-water ratio (CWR). The purpose of this study was to compare the CWR evaluated by using spectroscopic photoacoustic (sPA) imaging in cervical samples obtained from pregnant and non-pregnant women.

Methods

This cross-sectional study comprised cervical biopsies obtained at the time of hysterectomy (n = 8)

SUBMITTER: Yan Y 

PROVIDER: S-EPMC7928441 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature