Reassessment of the risk of birth defects due to Zika virus in Guadeloupe, 2016.

ABSTRACT:

Background

In the French Territories in the Americas (FTA), the risk of birth defects possibly associated with Zika virus (ZIKV) infection was 7.0% (95%CI: 5.0 to 9.5) among foetuses/infants of 546 women with symptomatic RT-PCR confirmed ZIKV infection during pregnancy. Many of these defects were isolated measurement-based microcephaly (i.e. without any detected brain or clinical abnormalities) or mild neurological conditions. We wanted to estimate the proportion of such minor findings among live births of women who were pregnant in the same region during the outbreak period but who were not infected with ZIKV.

Methods

In Guadeloupe, pregnant women were recruited at the time of delivery and tested for ZIKV infection. The outcomes of live born infants of ZIKV non-infected wom

SUBMITTER: Funk AL 

PROVIDER: S-EPMC7928479 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature