A Systematic Review and Meta-Analysis of Cancer Patients Affected by a Novel Coronavirus.

ABSTRACT:

Background

Cancer patients with coronavirus disease 2019 (COVID-19) have been reported to have double the case fatality rate of the general population.

Methods

A systematic search of PubMed, Embase, and Cochrane Central was done for studies on cancer patients with COVID-19. Pooled proportions were calculated for categorical variables. Odds ratio (OR) and forest plots (random-effects model) were constructed for both primary and secondary outcomes.

Results

This systematic review of 38 studies and meta-analysis of 181 323 patients from 26 studies included 23 736 cancer patients. Our meta-analysis shows that cancer patients with COVID-19 have a higher likelihood of death (n = 165 980, OR = 2.54, 95% confidence interval [CI] = 1.47 to 4.42), which was largely driven by mor

SUBMITTER: Venkatesulu BP 

PROVIDER: S-EPMC7928783 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature