What is the relationship between validated frailty scores and mortality for adults with COVID-19 in acute hospital care? A systematic review.

ABSTRACT:

Background and aim

The aim of this systematic review was to quantify the association between frailty and COVID-19 in relation to mortality in hospitalised patients.

Methods

Medline, Embase, Web of Science and the grey literature were searched for papers from inception to 10 September 2020; the search was re-run in Medline up until the 9 December 2020. Screening, data extraction and quality grading were undertaken by two reviewers. Results were summarised using descriptive statistics, including a meta-analysis of overall mortality; the relationships between frailty and COVID-19 mortality were summarised narratively.

Results

A total of 2,286 papers were screened resulting in 26 being included in the review. Most studies were from Europe, half from the UK, and one from B

SUBMITTER: Cosco TD 

PROVIDER: S-EPMC7929406 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature