Age and frailty are independently associated with increased COVID-19 mortality and increased care needs in survivors: results of an international multi-centre study.

ABSTRACT:

Introduction

Increased mortality has been demonstrated in older adults with coronavirus disease 2019 (COVID-19), but the effect of frailty has been unclear.

Methods

This multi-centre cohort study involved patients aged 18 years and older hospitalised with COVID-19, using routinely collected data. We used Cox regression analysis to assess the impact of age, frailty and delirium on the risk of inpatient mortality, adjusting for sex, illness severity, inflammation and co-morbidities. We used ordinal logistic regression analysis to assess the impact of age, Clinical Frailty Scale (CFS) and delirium on risk of increased care requirements on discharge, adjusting for the same variables.

Results

Data from 5,711 patients from 55 hospitals in 12 countries were included (median

SUBMITTER: Geriatric Medicine Research Collaborative 

PROVIDER: S-EPMC7929433 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature