Ramadan Fasting Leads to Shifts in Human Gut Microbiota Structured by Dietary Composition.

ABSTRACT: The structure and diversity of human gut microbiota are directly related to diet, though less is known about the influences of ethnicity and diet-related behaviors, such as fasting (intermittent caloric restriction). In this study, we investigated whether fasting for Ramadan altered the microbiota in Chinese and Pakistani individuals. Using high-throughput 16S rRNA gene sequencing and self-reported dietary intake surveys, we determined that both the microbiota and dietary composition were significantly different with little overlap between ethnic groups. Principal Coordinate Analyses (PCoA) comparison of samples collected from both groups before and after fasting showed partial separation of microbiota related to fasting in the Pakistani group, but not in the Chinese group. Measurement of

SUBMITTER: Ali I 

PROVIDER: S-EPMC7930080 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature